New therapeutic targets in aggressive B-cell lymphoma.
v. 02/09/2020
helped us to unveil gene signatures with high biological and clinic significance in our cancer models
Our objective
The final objective of their work is the design of individualized therapies, as it is intended that the information obtained can serve for the conduct of phase I/II clinical trials, in partnership with the biotechnology companies and the hemathology departments associated to their projects.
The project "New therapies against oncogenes and tumoral microenvironment in B-cell aggressive lymphomas" is funded by the Carlos III Health Institute (ISCIII).
A large amount of data from several gene expression analysis techniques and tumor groups was gathered.
To identify the best genetic biomarkers to classify the different groups, we needed to automatically integrate all these data sets.
This integrative approach was not easily available in the classical analysis software tools, at least in an efficient manner.
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helped them
to unveil gene signatures
with high biological and clinic significance in their cancer models.
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Features
The key features of
applied to this work were
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